Fundamental Research Health Science Highlights

Smartly solved: How molecules release active ingredients in a targeted way

Smart molecules can change their shape and properties depending on temperature or other parameters such as macromolecular architecture. In pharmaceutic applications, they release active ingredients in a targeted manner at the desired locations. Neutrons at the MLZ reveal these nanostructures and help specifically design new molecules with desired properties.

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Health Science Highlights

Small-angle scattering techniques offer new insight towards the treatment of Alzheimer’s disease

Aggregates of amyloid beta- (Aβ-)peptide, known as fibrils, are one of the hallmarks of Alzheimer’s disease and play a key role in the sequence of events leading to dementia symptoms. Using small-angle neutron and X-ray scattering, researchers from Lund University and the Paul Scherrer Institut have determined the detailed structure of Aβ42-fibril, obtaining important information to design future therapeutics.

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